When a boy with a terrible secret moves to town there is a sudden increase in dust storms, and asthmatic Avalyn theorizes the storms are linked to his emotions and tries to help as she struggles to breathe.

The dust bunnies try to help a big, mean dust bully smile by playing a rhyming game with him.

Horton is a the lovable elephant who tries to protect tiny creatures on a speck of dust. It seems that he is the only one who can hear the tiny people of the tiny planet.

Zarina, an ambitious dust keeper, is captivated by Blue Pixie Dust and its wonderful possibilities. Zarina's wild ideas lead to trouble, and she flees to Skull Rock, where she joins forces with a band of pirates. Tinker Bell and her friends embark on a mission to save Zarina and return her to Pixie Hollow. Adventures include crossing swords with a pirate cabin boy names James, who will soon become Captain Hook.