Acquiring superpowers through a genetics experiment gone awry, four best friends including girly Cheri, tough Scarlet, shy Opaline and peacemaker Iris become fashionable champions for justice while their scientist mothers diligently work in the secret lab where their powers were created.

What happens when four best friends find themselves splattered with a bubbling, genetically altering substance during a seemingly innocent sleepover in a secret, see-through, high-tech, futuristic lab? They develop superpowers, that's what! Iris, Cheri, Scarlet, and sometimes Opaline have become . . .the Ultra Violets.