Jefferson Smith is a small town idealist who answers the call to duty when he's unexpectedly named to fill a vacant seat in the U.S. Senate. Determined to do some good, he sponsors a bill to create a national boy's camp, unaware it threatens to undermine a graft scheme sponsored by his home state's crooked political machine. Framed and threatened with expulsion, Jefferson takes to the Senate floor to prove his innocence.

Follows the adventures of "good old boy" cousins Bo and Luke Duke, who with the help of their eye-catching cousin Daisy and moonshine-running Uncle Jesse, try and save the family farm from being destroyed by Hazzard County's corrupt commissioner Boss Hogg.