Follows the young homicide detective/psychologist as he meets his match in a serial killer. The two face off in a high-stakes game of cat and mouse, but when the mission gets personal, Cross is pushed to the edge of his moral and psychological limits in this taut and exciting action thriller.

Washington DC detective Dr. Alex Cross (Morgan Freeman) travels to North Carolina to investigate the apparent kidnapping of his niece (Gina Ravera). Aided by escaped kidnapee Kate McTiernan (Ashley Judd), Cross hunts down the kidnapper, who operates under the pseudonym "Cassanova".

Psychotherapist Dr. Sam Rice's life is upset by the savage murder of his client Bynum. The antique dealer is the victim of a female Jack The Ripper, and Rice may be next. The alluring Brooke Reynolds walks out of Bynum's past and quickly becomes part of Rice's life. As Rice falls in love with the deeply-troubled Brooke, the evidence points to her as the murderer.