The kids in Room 207 take advantage of their teacher's good nature until she disappears and they are faced with a vile substitute.

A.J. and his friends launch their own investigation when they get stuck with weird substitute Ms. Todd, and begin to suspect she has kidnapped their regular teacher in order to take over the job.

The very literal minded Amelia Bedelia becomes a substitute teacher for a day.

Lilly loves everything about school, especially her teacher, but when he asks her to wait a while before showing her new purse, she does something for which she is very sorry later.

Will Lizzie Glick, a high-spirited Amish teenager, give up her dream of teaching school so that her wish for a family and a marriage can come true? Based on the true experiences of the author's extended family.

"A.J. and his friends are starting fourth grade. A new school year means a new teacher, and Miss Banks may be their weirdest one yet. She won't stop playing practical jokes on the class, and A.J. has reached his breaking point. Will he and the gang learn to not fall for their teacher's tricks? Or will Miss Banks prevail as the ultimate prankster?"--

"The two best friends come across an enthusiastic school of fish one morning. Unfortunately, Mr. Blowfish, their teacher, has come down with a cold, and class will have to be cancelled ... until Professor Knowell (Narwhal) and Super Teacher (Jelly) volunteer to help out! The first subject is Wafflematics, in which Narwhal and Jelly calculate the number of waffles needed to feed the class. That's what we're chalking about! Next up is a super-fun science...

Oh no! Mr. Granite is sick. A. J. and the gang will have a substitute teacher all week. Yay! But Miss Kraft is weird. She wears a clown costume and uses hand puppets to talk. She likes to do magic tricks. And she's happy all the time. What is her problem?

When Ella Mentry School holds a science fair, Dr. Snow arrives to help A.J. and his friends conduct their experiments.

Unusual things continue to happen in the classroom on the thirtieth floor of Wayside School, which was accidentally built sideways with one classroom on each story. "Before you enter Wayside School, you should know that it's a thirty-story building with one classroom on each floor. Mrs. Jewls teaches the class on the thirtieth story. Mis Zaves teaches the class on the nineteeth story -- except there is no nineteenth story, so there is no Miss Zarves....